Do Weight Loss Medications Really Work? Yes, weight loss medication can help you lose weight in the short term. One of the biggest challenges in obesity is not just hunger it is mental hunger, also known as food noise. Food noise is the constant thinking about food: Cravings throughout the day Urge to snack frequently Difficulty controlling portions Medications help reduce t... https://www.freedomfromdiabetes.org/blog/post/weight-loss-medication-shortcut-or-6-month-change/5212