Objective: Chemotherapy is one of the important adjuvant methods for the treatment of glioblastoma (GBM). and chemotherapy resistance is a clinical problem that neurooncologists need to solve urgently. It is reported that Saikosaponin D (SSD). an active component of Bupleurum chinense. https://www.jmannino.com/mega-save-KangVape-Onee-Stick-Disposable-3000-Puffs-12mL-special-find/